We provide research and project management support to advance small molecule programs from early-lead to Phase one clinical trials. We leverage our internal resources in conjunction with the resources of our network of in vitro pharmacology, ADME, toxicology and pharmaceutics CROs to provide support for our partners.
What we offer:
HIGH QUALITY
We operate seamlessly with our partners as part of a unified research team to provide support from an experienced team of professionals with a successful track record of advancing projects from drug discovery into clinical trials
TIME EFFICIENCY
Reduce the time that it takes to achieve project milestones by leveraging an integrated and experienced drug discovery team working in combination with a network of trusted strategic partners and consultants
COST EFFECTIVENESS
By sharing the overhead costs of building and maintaining a state-of-the-art research facility
Services:
CHEMISTRY
Lead optimization, multigram compound synthesis for preclinical activities, synthesis of tools and benchmark molecules
DMPK
In vitro and in vivo pharmacokinetic determination, metabolism ID, CYP inhibition
PERSONALIZED PROJECT MANAGEMENT
Discussion and implementation of research plans, including target product profiles, optimization flowcharts, and intellectual property strategy
QUANTITATIVE BIOLOGY
Assay optimization and automation compound optimization support
STRUCTURAL BIOLOGY/
COMPUTATIONAL CHEMISTRY
X-ray crystal structure elucidation, docking and QSAR
Equipped with state of the art analytical instrumentation housed in 20,000 square feet in South San Francisco, including 2 chemistry labs with a total of 18 hoods,
biology lab, tissue culture lab,
DMPK lab, and vivarium.
