Peptide inhibitors of TRIM7 and uses thereof

By: Schreiber, Taylor; Fromm, George; Nguyen, Thuy-Ai; Medina, Julio Cesar; Mendoza, Angel; Valles, Daniel; Szeto, Judy

Patent Number: WO2025188614 A1/A8

Publication Date: 2025-10-02

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Preparation of quinazolinamines, isoquinolinamines, oxoindolinamines and related derivatives as SARM1 inhibitors

By: Medina, Julio Cesar; Singha Roy, Moumita; Li, Guo; Hu, Chaowei; Mendoza, Angel; Wang, Pengzhi; Tegley, Christopher Michael; Reynolds, Charles Howard

Patent Number: WO2025207539 A1

Publication Date: 2025-10-02

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Preparation of bicyclic heteroaryl compounds as TREM2 activators

By: Grice, Cheryl A; Tasker, Andrew Stewart; Medina, Julio Cesar; Xu, Shiyan; Shrestha, Anuska; Tegley, Christopher Michael; Singha Roy, Moumita; Bhatt, Ulhas; Avullala, Thirupataiah; Li, Guo; Bone, Kendelyn; Hu, Chaowei

Patent Number: WO2025117599 A1

Publication Date: 2025-06-05

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​Preparation of indolin-2-one derivatives as SARM1 inhibitors

By: Medina, Julio Cesar; Singha Roy, Moumita; Li, Guo; Hu, Chaowei; Tegley, Christopher Michael; Tasker, Andrew Stewart; Reynolds, Charles Howard

Patent Number: WO2025090514 A1

Publication Date: 2025-05-01

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Preparation of carboxybenzamides and related compounds as TRIM7 inhibitors and uses thereof

By: Schreiber, Taylor; Fromm, George; Nguyen, Thuy-Ai; Medina, Julio Cesar; Mendoza, Angel; Szeto, Judy

Patent Number: WO2025042798 A1

Publication Date: 2025-02-27

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Preparation of tetrahydroisoquinolin-1-ones and related compounds as TRIM7 inhibitors and uses thereof

By: Schreiber, Taylor; Fromm, George; Nguyen, Thuy-Ai; Medina, Julio Cesar

Patent Number: WO2025042797 A1

Publication Date: 2025-02-27

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​Preparation of opioid receptor modulators and uses thereof

By: Medina, Julio Cesar; Nerurkar, Alok; Sadlowski, Corinne; Seidl, Frederick; Cheng, Heng; Duquette, Jason; Lee, John; Holan, Martin; Ding, Pingyu; Wang, Xiaodong; Widjaja, Tien; Nguyen, Thomas; Bhatt, Ulhas; Li, Yihong; Wei, Zhi-Liang

Patent Number: WO2022216750 A1

Publication Date: 2022-10-13

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Preparation of fluoroalkyl-oxadiazoles as selective HDAC6 inhibitors and uses thereof

By: Mandegar, Mohammad A.; Patel, Snahel; Ding, Pingyu; Bhatt, Ulhas; Holan, Martin; Lee, John; Li, Yihong; Medina, Julio; Nerurkar, Alok; Seidl, Frederick; Sperandio, David; Widjaja, Tien

Patent Number: WO2021127643 A1

Publication Date: 2021-06-24

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Preparation of 5-fluoronicotinamide derivatives as selective HDAC6 inhibitors for treating heart diseases

By: Mandegar, Mohammad A.; Patel, Snahel; Bhatt, Ulhas; Ding, Pingyu; Holan, Martin; Lee, John; Li, Yihong; Medina, Julio; Nerurkar, Alok; Seidl, Frederick; Sperandio, David; Widjaja, Tien; Wang, Xiaodong

Patent Number: WO2021067859 A1

Publication Date: 2021-04-08

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Preparation of dialkylaminomethyl- carbamates, ureas, and amides. Opioid receptor modulators and products and methods related thereto

By: Medina, Julio Cesar; McGee, Larry; Wei, Zhi-Liang; Sadlowski, Corinne; Seidl, Frederick; Bhatt, Ulhas; Wang, Xiaodong; Nguyen, Thomas; Sperandio, David; Ding, Pingyu; Nerurkar, Alok; Li, Yihong; Duquette, Jason

Patent Number: WO2019195634 A1

Publication Date: 2019-10-10

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